Basic Information
ID: ALA5209836
Type: Functional
Description: GPCR beta-arrestin recruitment assay with target: S1PR1 Assay Type: PRESTO-Tango Concentration: 0.00001
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5209836
%Inhib (Mean)
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 303.29 | 1.77 | 1.77 |
| 437.56 | 1.20 | 1.20 |
| 412.51 | 3.52 | 3.52 |
| 232.28 | 1.86 | 1.86 |
| 555.63 | -0.16 | -0.16 |
| 302.37 | 3.57 | 3.57 |
| 187.15 | -1.50 | -1.50 |
| 185.18 | -0.49 | -0.49 |
| 510.63 | 4.69 | 4.69 |
| 506.51 | 3.85 | 3.85 |
| 398.47 | 3.96 | 3.96 |
| 408.46 | 3.74 | 3.74 |
| 267.25 | -1.98 | -1.98 |
| 309.41 | 3.44 | 3.44 |
| 380.49 | 6.09 | 6.09 |
| 354.49 | 3.48 | 3.48 |
| 316.43 | 0.50 | 0.50 |
| 248.33 | 1.91 | 1.91 |
| 354.41 | 1.71 | 1.71 |
| 312.43 | 0.33 | 0.33 |
| 285.39 | 2.66 | 2.66 |
| 477.58 | 5.48 | 5.48 |
| 584.74 | 4.47 | 4.47 |
| 353.37 | 4.42 | 4.42 |
| 144.21 | 2.29 | 2.29 |
| 360.46 | 3.59 | 3.59 |
| 463.80 | 5.94 | 5.94 |
| 281.48 | 5.51 | 5.51 |
| 403.98 | 3.94 | 3.94 |
| 486.53 | 3.26 | 3.26 |
| 575.69 | 5.70 | 5.70 |
| 455.97 | 3.43 | 3.43 |
| 520.63 | 5.58 | 5.58 |
| 481.51 | 4.63 | 4.63 |
| 510.68 | 5.56 | 5.56 |
| 265.36 | 2.48 | 2.48 |
| 272.39 | 3.61 | 3.61 |
| 183.21 | 0.35 | 0.35 |
| 296.15 | 4.36 | 4.36 |
| 388.90 | 4.23 | 4.23 |
| 221.30 | 3.15 | 3.15 |
| 435.61 | 4.54 | 4.54 |
| 495.54 | 3.07 | 3.07 |
| 507.59 | 3.85 | 3.85 |
| 183.10 | -1.03 | -1.03 |
| 402.87 | 5.26 | 5.26 |
| 183.10 | -1.03 | -1.03 |
| 358.18 | 2.46 | 2.46 |
| 279.38 | 3.66 | 3.66 |
| 266.73 | 2.51 | 2.51 |
| 292.38 | 3.44 | 3.44 |
| 393.51 | 1.60 | 1.60 |
| 507.59 | 5.44 | 5.44 |
| 354.49 | 3.04 | 3.04 |
| 424.92 | 3.20 | 3.20 |
| 357.17 | 3.24 | 3.24 |
| 463.63 | 4.54 | 4.54 |
| 278.40 | 3.92 | 3.92 |
| 502.56 | 5.90 | 5.90 |
| 473.94 | 6.05 | 6.05 |
| 356.47 | 2.78 | 2.78 |
| 480.65 | 4.94 | 4.94 |
| 715.92 | 2.89 | 2.89 |
| 337.46 | -0.77 | -0.77 |
| 340.85 | 4.30 | 4.30 |
| 379.46 | 2.25 | 2.25 |
| 270.21 | 3.25 | 3.25 |
| 392.46 | 4.11 | 4.11 |
| 214.18 | 0.16 | 0.16 |
| 335.36 | -0.21 | -0.21 |
| 354.45 | 4.61 | 4.61 |
| 573.69 | 5.95 | 5.95 |
| 440.46 | 4.03 | 4.03 |
| 514.63 | 7.26 | 7.26 |
| 373.47 | 3.83 | 3.83 |
| 381.49 | 4.27 | 4.27 |
| 383.47 | 3.02 | 3.02 |
| 425.53 | 3.70 | 3.70 |
| 610.71 | 0.83 | 0.83 |
| 435.53 | 4.16 | 4.16 |
| 466.59 | 4.19 | 4.19 |
| 554.65 | 5.61 | 5.61 |
| 620.51 | 3.30 | 3.30 |
| 403.83 | 4.37 | 4.37 |
| 353.37 | 2.82 | 2.82 |
| 307.48 | 3.20 | 3.20 |
| 294.36 | 2.41 | 2.41 |
| 378.43 | 3.52 | 3.52 |
| 556.36 | 5.37 | 5.37 |
| 841.99 | -0.02 | -0.02 |
| 508.62 | 4.48 | 4.48 |
| 337.34 | 1.72 | 1.72 |
| 359.73 | 2.43 | 2.43 |
| 367.88 | 2.09 | 2.09 |
| 441.59 | 5.59 | 5.59 |
| 510.29 | 0.41 | 0.41 |
| 378.55 | 5.03 | 5.03 |
| 569.66 | 0.23 | 0.23 |
| 438.44 | 5.79 | 5.79 |
| 316.49 | 3.93 | 3.93 |
| 524.67 | 7.25 | 7.25 |
| 167.21 | 0.65 | 0.65 |
| 259.35 | 2.57 | 2.57 |
| 448.95 | 5.68 | 5.68 |
| 239.18 | 0.17 | 0.17 |
| 1632.29 | ||
| 412.58 | 5.08 | 5.08 |
| 415.57 | 4.11 | 4.11 |
| 315.48 | 4.27 | 4.27 |
| 361.53 | 5.33 | 5.33 |
| 604.75 | 3.41 | 3.41 |
| 388.38 | 4.39 | 4.39 |
| 325.41 | 3.95 | 3.95 |
| 416.47 | 3.09 | 3.09 |
| 539.65 | 2.98 | 2.98 |
| 600.79 | 4.27 | 4.27 |
| 283.39 | 2.06 | 2.06 |
| 244.24 | 3.42 | 3.42 |
| 364.41 | 4.66 | 4.66 |
| 387.46 | 3.32 | 3.32 |
| 356.60 | 4.81 | 4.81 |
| 994.21 | -3.04 | -3.04 |
| 476.06 | 6.81 | 6.81 |
| 578.60 | 6.79 | 6.79 |
| 347.41 | 5.11 | 5.11 |
| 402.39 | 4.84 | 4.84 |
| 384.87 | 4.60 | 4.60 |
| 482.01 | 5.25 | 5.25 |
| 343.46 | 2.58 | 2.58 |
| 392.47 | 1.90 | 1.90 |
| 304.39 | 2.36 | 2.36 |
| 175.24 | 2.14 | 2.14 |
| 435.90 | 4.39 | 4.39 |
| 536.45 | 5.72 | 5.72 |
| 440.37 | 7.17 | 7.17 |
| 379.48 | 4.04 | 4.04 |
| 364.94 | 5.24 | 5.24 |
| 394.85 | 3.31 | 3.31 |
| 434.90 | 3.08 | 3.08 |
| 534.43 | 4.95 | 4.95 |
| 337.45 | 3.82 | 3.82 |
| 312.46 | 2.75 | 2.75 |
| 362.39 | -1.81 | -1.81 |
| 566.53 | 3.69 | 3.69 |
| 290.37 | 3.70 | 3.70 |
| 376.58 | 5.51 | 5.51 |
| 496.63 | 3.90 | 3.90 |
| 416.88 | 3.19 | 3.19 |
| 266.69 | 1.29 | 1.29 |
| 422.92 | 4.27 | 4.27 |
| 522.58 | 2.01 | 2.01 |
| 411.87 | 4.76 | 4.76 |
| 428.54 | 4.78 | 4.78 |
| 411.63 | 5.00 | 5.00 |
| 517.61 | 5.68 | 5.68 |
| 309.30 | 2.86 | 2.86 |
| 361.40 | 0.02 | 0.02 |
| 1550.86 | ||
| 492.31 | 5.42 | 5.42 |
| 446.43 | 3.25 | 3.25 |
| 603.70 | 4.70 | 4.70 |
| 424.54 | 3.05 | 3.05 |
| 500.48 | 4.11 | 4.11 |
| 400.89 | 3.26 | 3.26 |
| 476.57 | 3.09 | 3.09 |
| 593.67 | 4.54 | 4.54 |
| 189.64 | 0.60 | 0.60 |
| 419.87 | 1.78 | 1.78 |
| 289.38 | 1.93 | 1.93 |
| 445.49 | 4.12 | 4.12 |
| 447.62 | 6.09 | 6.09 |
| 587.08 | 5.77 | 5.77 |
| 281.33 | 4.14 | 4.14 |
| 421.31 | 4.71 | 4.71 |
| 539.37 | 4.37 | 4.37 |
| 269.35 | 1.48 | 1.48 |
| 400.28 | 2.82 | 2.82 |
| 321.34 | 2.00 | 2.00 |
| 536.68 | 5.19 | 5.19 |
| 425.51 | 4.01 | 4.01 |
| 397.56 | 5.91 | 5.91 |
| 376.46 | 1.42 | 1.42 |
| 492.59 | 5.63 | 5.63 |
| 491.63 | 6.81 | 6.81 |
| 402.66 | 6.36 | 6.36 |
| 295.81 | 2.58 | 2.58 |
| 358.42 | 2.66 | 2.66 |
| 336.23 | 2.38 | 2.38 |
| 398.73 | 3.68 | 3.68 |
| 653.58 | 5.54 | 5.54 |
| 327.43 | 1.71 | 1.71 |
| 264.32 | 3.41 | 3.41 |
| 421.51 | 2.91 | 2.91 |
| 401.00 | 5.59 | 5.59 |
| 452.29 | 5.34 | 5.34 |
| 447.97 | 5.52 | 5.52 |
| 343.90 | 2.39 | 2.39 |
| 300.83 | 3.08 | 3.08 |
| 316.88 | 3.88 | 3.88 |
| 488.46 | 4.08 | 4.08 |
| 379.88 | 4.70 | 4.70 |
| 539.26 | 0.42 | 0.42 |
| 266.56 | 2.36 | 2.36 |
| 513.51 | 5.09 | 5.09 |
| 584.68 | 6.55 | 6.55 |
| 535.99 | -0.16 | -0.16 |
| 212.68 | 1.37 | 1.37 |
| 252.75 | 1.77 | 1.77 |
| 454.01 | 4.18 | 4.18 |
| 425.92 | 1.35 | 1.35 |
| 510.43 | 4.22 | 4.22 |
| 348.38 | 4.31 | 4.31 |
| 361.23 | 5.23 | 5.23 |
| 630.12 | 2.87 | 2.87 |
| 412.28 | 5.21 | 5.21 |
| 418.54 | 3.73 | 3.73 |
| 319.45 | 3.88 | 3.88 |
| 406.42 | 3.60 | 3.60 |
| 454.57 | 6.79 | 6.79 |
| 392.50 | 3.15 | 3.15 |
| 353.45 | 2.48 | 2.48 |
| 290.18 | 1.72 | 1.72 |
| 442.23 | 1.76 | 1.76 |
| 296.84 | 2.85 | 2.85 |
| 506.48 | 3.55 | 3.55 |
| 282.56 | 1.55 | 1.55 |
| 521.05 | 4.09 | 4.09 |
| 679.80 | 2.08 | 2.08 |
| 284.36 | 2.21 | 2.21 |
| 538.13 | 5.51 | 5.51 |
| 608.18 | 8.95 | 8.95 |
| 393.88 | 6.14 | 6.14 |
| 340.29 | 4.19 | 4.19 |
| 296.84 | 2.85 | 2.85 |
| 459.97 | 5.10 | 5.10 |
| 418.37 | 4.30 | 4.30 |
| 475.58 | 5.34 | 5.34 |
| 390.87 | 3.82 | 3.82 |
| 361.92 | 2.29 | 2.29 |
| 345.79 | 4.44 | 4.44 |
| 451.62 | 3.19 | 3.19 |
| 377.87 | 1.53 | 1.53 |
| 632.66 | 5.77 | 5.77 |
| 523.69 | 5.62 | 5.62 |
| 698.26 | 3.82 | 3.82 |
| 283.40 | 4.17 | 4.17 |
| 324.25 | 3.67 | 3.67 |
| 358.36 | -0.24 | -0.24 |
| 501.84 | 4.29 | 4.29 |
| 313.87 | 2.61 | 2.61 |
| 388.96 | 2.67 | 2.67 |
| 319.32 | 0.77 | 0.77 |
| 315.80 | 0.98 | 0.98 |
| 530.41 | 2.91 | 2.91 |
| 365.90 | 3.26 | 3.26 |
| 419.35 | 3.36 | 3.36 |
| 368.47 | 2.66 | 2.66 |
| 390.91 | 2.65 | 2.65 |
| 472.69 | 5.21 | 5.21 |
| 794.86 | -0.24 | -0.24 |
| 356.38 | 4.53 | 4.53 |
| 453.36 | 5.42 | 5.42 |
| 394.47 | 3.81 | 3.81 |
| 408.29 | 4.25 | 4.25 |
| 230.31 | 2.68 | 2.68 |
| 491.60 | 3.57 | 3.57 |
| 219.29 | 1.17 | 1.17 |
| 323.82 | 2.35 | 2.35 |
| 482.58 | 4.66 | 4.66 |
| 198.10 | 0.30 | 0.30 |
| 364.90 | 3.50 | 3.50 |
| 448.13 | -2.62 | -2.62 |
| 545.49 | 5.00 | 5.00 |
| 464.63 | 4.14 | 4.14 |
| 413.15 | 3.77 | 3.77 |
| 332.06 | 0.58 | 0.58 |
| 417.47 | 2.81 | 2.81 |
| 184.07 | -0.09 | -0.09 |
| 249.27 | 3.41 | 3.41 |
| 331.81 | 2.49 | 2.49 |
| 402.76 | 2.28 | 2.28 |
| 354.84 | 3.31 | 3.31 |
| 478.00 | 4.03 | 4.03 |
| 310.46 | 2.92 | 2.92 |
| 450.51 | 5.35 | 5.35 |
| 432.95 | 6.27 | 6.27 |
| 878.24 | -4.19 | -4.19 |
| 477.52 | 2.75 | 2.75 |
| 438.45 | 6.53 | 6.53 |
| 524.64 | 5.31 | 5.31 |
| 283.36 | 3.16 | 3.16 |
| 423.63 | 3.98 | 3.98 |
| 386.49 | 3.30 | 3.30 |
| 407.74 | 2.68 | 2.68 |
| 388.88 | 4.80 | 4.80 |
| 415.37 | 4.74 | 4.74 |
| 479.56 | 2.72 | 2.72 |
| 646.18 | 6.02 | 6.02 |
| 316.45 | 4.66 | 4.66 |
| 793.43 | 6.34 | 6.34 |
| 549.07 | 4.00 | 4.00 |
| 463.88 | 4.34 | 4.34 |
| 568.60 | 3.31 | 3.31 |
| 509.70 | 4.28 | 4.28 |
| 496.04 | 3.61 | 3.61 |
| 164.16 | 0.77 | 0.77 |
| 364.42 | 5.40 | 5.40 |
| 302.13 | 2.16 | 2.16 |
| 396.52 | 2.77 | 2.77 |
| 245.32 | 2.25 | 2.25 |
| 523.96 | 3.09 | 3.09 |
| 588.28 | 3.57 | 3.57 |
| 412.90 | 3.18 | 3.18 |
| 414.96 | 2.41 | 2.41 |
| 485.51 | 5.82 | 5.82 |
| 433.58 | 4.72 | 4.72 |
| 624.78 | 1.77 | 1.77 |
| 236.75 | 3.18 | 3.18 |
| 988.18 | -2.46 | -2.46 |
| 649.71 | 4.50 | 4.50 |
| 340.29 | 4.63 | 4.63 |
| 478.53 | 3.12 | 3.12 |
| 407.92 | 3.50 | 3.50 |
| 448.52 | 5.15 | 5.15 |
| 414.55 | 4.14 | 4.14 |
| 427.56 | 4.67 | 4.67 |
| 320.40 | 3.70 | 3.70 |
| 379.41 | 1.34 | 1.34 |
| 283.42 | 3.12 | 3.12 |
| 284.23 | 2.95 | 2.95 |
| 534.57 | 4.49 | 4.49 |
| 444.94 | 4.30 | 4.30 |
| 400.45 | 5.08 | 5.08 |
| 399.49 | 5.12 | 5.12 |
| 484.37 | 5.85 | 5.85 |
| 482.54 | 5.67 | 5.67 |
| 390.30 | 1.19 | 1.19 |
| 398.96 | 1.29 | 1.29 |
| 342.75 | 2.78 | 2.78 |
| 403.58 | 4.34 | 4.34 |
| 503.52 | 5.63 | 5.63 |
| 324.40 | 3.62 | 3.62 |
| 307.32 | 3.31 | 3.31 |
| 444.77 | 4.86 | 4.86 |
| 342.35 | 3.42 | 3.42 |
| 470.55 | 2.30 | 2.30 |
| 265.32 | 2.01 | 2.01 |
| 405.50 | 3.38 | 3.38 |
| 475.00 | 4.53 | 4.53 |
| 330.34 | 3.43 | 3.43 |
| 740.26 | 6.43 | 6.43 |
| 377.37 | 3.28 | 3.28 |
| 441.91 | 3.66 | 3.66 |
| 685.87 | 5.71 | 5.71 |
| 464.99 | 6.31 | 6.31 |
| 426.42 | 3.44 | 3.44 |
| 284.26 | 1.58 | 1.58 |
| 436.97 | 2.50 | 2.50 |
| 447.83 | 3.06 | 3.06 |
| 456.57 | 3.95 | 3.95 |
| 453.33 | 4.18 | 4.18 |
| 520.04 | 5.51 | 5.51 |
| 338.49 | 4.50 | 4.50 |
| 429.31 | 3.46 | 3.46 |
| 161.64 | 0.22 | 0.22 |
| 512.68 | 4.62 | 4.62 |
| 488.49 | 6.31 | 6.31 |
| 469.55 | 3.57 | 3.57 |
| 319.34 | 3.50 | 3.50 |
| 351.43 | 4.17 | 4.17 |
| 452.49 | 2.89 | 2.89 |
| 461.91 | 4.20 | 4.20 |
| 392.89 | 5.65 | 5.65 |
| 418.91 | 3.22 | 3.22 |
| 485.01 | 5.05 | 5.05 |
| 457.49 | 6.93 | 6.93 |
| 391.78 | 4.84 | 4.84 |
| 490.44 | 2.35 | 2.35 |
| 490.94 | 6.91 | 6.91 |
| 316.79 | 2.95 | 2.95 |
| 365.39 | 3.32 | 3.32 |
| 483.39 | 5.36 | 5.36 |
| 416.53 | 4.02 | 4.02 |
| 404.47 | 3.63 | 3.63 |
| 500.48 | 5.73 | 5.73 |
| 506.50 | 5.27 | 5.27 |
| 366.24 | 4.09 | 4.09 |
| 410.67 | 3.64 | 3.64 |
| 597.76 | 4.84 | 4.84 |
| 276.74 | 2.82 | 2.82 |
| 405.84 | 5.49 | 5.49 |
| 461.56 | 4.91 | 4.91 |
| 459.93 | 1.06 | 1.06 |
| 332.31 | 4.17 | 4.17 |
| 379.45 | 2.44 | 2.44 |
| 406.43 | 4.87 | 4.87 |
| 566.49 | 3.26 | 3.26 |
| 341.24 | 2.12 | 2.12 |
| 511.97 | 7.36 | 7.36 |
| 391.77 | 4.01 | 4.01 |
| 573.68 | 5.14 | 5.14 |
| 419.96 | 5.18 | 5.18 |
| 319.32 | 0.47 | 0.47 |
| 340.43 | 3.06 | 3.06 |
| 470.92 | 2.74 | 2.74 |
| 459.42 | 4.88 | 4.88 |
| 591.24 | 1.52 | 1.52 |
| 327.06 | 0.95 | 0.95 |
| 550.09 | -2.50 | -2.50 |
| 326.31 | -1.84 | -1.84 |
| 420.34 | 2.57 | 2.57 |
| 236.73 | 2.25 | 2.25 |
| 331.89 | 4.02 | 4.02 |
| 382.33 | 3.21 | 3.21 |
| 352.47 | 3.25 | 3.25 |
| 599.56 | 3.15 | 3.15 |
| 610.27 | -4.79 | -4.79 |
| 526.51 | 1.67 | 1.67 |
| 448.39 | 4.20 | 4.20 |
| 398.50 | 4.01 | 4.01 |
| 757.69 | 2.05 | 2.05 |
| 488.14 | 5.28 | 5.28 |
| 337.28 | 0.09 | 0.09 |
| 323.06 | -0.90 | -0.90 |
| 374.98 | 3.13 | 3.13 |
| 464.01 | 5.29 | 5.29 |
| 759.83 | 1.11 | 1.11 |
| 293.80 | 2.73 | 2.73 |
| 451.35 | 2.79 | 2.79 |
| 523.03 | 5.22 | 5.22 |
| 285.77 | 1.94 | 1.94 |
| 568.50 | 3.09 | 3.09 |
| 493.09 | 6.54 | 6.54 |
| 445.97 | 4.76 | 4.76 |
| 646.23 | -4.70 | -4.70 |
| 468.47 | 3.52 | 3.52 |