Basic Information
ID: ALA5216101
Type: Binding
Description: Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incubated for 1 hrs using m3T nucleoside as substrate by LCMS-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5216101
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.67 | 1.41 | 1.41 |
| 196.16 | -0.40 | -0.40 |
| 322.32 | 2.42 | 2.42 |
| 272.26 | 1.27 | 1.27 |
| 348.36 | 2.94 | 2.94 |
| 323.31 | 1.82 | 1.82 |