Basic Information
ID: ALA5216102
Type: Binding
Description: Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incubated for 30 mins using 5-mer ssRNA oligonucleotide [GG(m6A)CU] as substrate by LCMS-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5216102
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.32 | 1.07 | 1.07 |
| 322.32 | 2.42 | 2.42 |
| 272.26 | 1.27 | 1.27 |
| 345.31 | 1.13 | 1.13 |
| 344.33 | 0.70 | 0.70 |
| 348.36 | 2.94 | 2.94 |
| 332.27 | 1.25 | 1.25 |
| 323.31 | 1.82 | 1.82 |
| 333.26 | 0.65 | 0.65 |
| 303.28 | 0.32 | 0.32 |
| 358.35 | 1.05 | 1.05 |
| 302.29 | 0.93 | 0.93 |