Basic Information
ID: ALA5216104
Type: Binding
Description: Inhibition of recombinant N-terminal hexahistidine-tagged human PDH2 (181 to 426 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by substrate addition and measured after 15 mins using CODD peptide DLDLEMLAPYIPMDDDFQL as substrate by SPE-MS-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5216104
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.32 | 1.07 | 1.07 |
| 337.34 | 2.50 | 2.50 |
| 272.26 | 1.27 | 1.27 |
| 345.31 | 1.13 | 1.13 |
| 331.28 | 1.04 | 1.04 |
| 344.33 | 0.70 | 0.70 |
| 348.36 | 2.94 | 2.94 |
| 332.27 | 1.25 | 1.25 |
| 323.31 | 1.82 | 1.82 |
| 333.26 | 0.65 | 0.65 |
| 358.35 | 1.05 | 1.05 |
| 302.29 | 0.93 | 0.93 |