Basic Information
ID: ALA5216111
Type: Binding
Description: Binding affinity to BRD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as thermal stabilization at 10 uM by SYPRO orange dye based DSF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5216111
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 163.18 | 0.50 | 0.50 |
| 214.23 | 0.80 | 0.80 |
| 174.20 | 2.23 | 2.23 |
| 248.34 | 2.28 | 2.28 |
| 229.31 | 3.02 | 3.02 |
| 281.33 | 0.56 | 0.56 |
| 253.35 | 1.10 | 1.10 |
| 261.67 | 2.46 | 2.46 |
| 221.28 | 1.72 | 1.72 |
| 262.28 | -1.30 | -1.30 |
| 221.25 | 1.32 | 1.32 |
| 243.23 | 1.21 | 1.21 |
| 235.31 | 2.68 | 2.68 |
| 305.19 | 2.73 | 2.73 |
| 266.33 | 2.35 | 2.35 |
| 209.23 | 0.97 | 0.97 |
| 199.21 | 2.53 | 2.53 |
| 194.20 | -1.48 | -1.48 |
| 264.31 | 2.27 | 2.27 |
| 269.76 | 3.22 | 3.22 |
| 239.30 | 1.20 | 1.20 |
| 201.19 | 1.25 | 1.25 |
| 310.40 | 1.54 | 1.54 |
| 198.27 | 2.40 | 2.40 |