ID: ALA5216112
Type: Binding
Description: Inhibition of BRD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [Lys(Ac)5/8/12/16]-histone H4 (1 to 21residues)-GGK as substrate incubated for 30 mins by TR-FRET assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA5216112
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
163.18 | 0.50 | 0.50 |
214.23 | 0.80 | 0.80 |
174.20 | 2.23 | 2.23 |
248.34 | 2.28 | 2.28 |
229.31 | 3.02 | 3.02 |
281.33 | 0.56 | 0.56 |
253.35 | 1.10 | 1.10 |
261.67 | 2.46 | 2.46 |
221.28 | 1.72 | 1.72 |
262.28 | -1.30 | -1.30 |
221.25 | 1.32 | 1.32 |
243.23 | 1.21 | 1.21 |
235.31 | 2.68 | 2.68 |
305.19 | 2.73 | 2.73 |
266.33 | 2.35 | 2.35 |
209.23 | 0.97 | 0.97 |
199.21 | 2.53 | 2.53 |
194.20 | -1.48 | -1.48 |
264.31 | 2.27 | 2.27 |
269.76 | 3.22 | 3.22 |
239.30 | 1.20 | 1.20 |
201.19 | 1.25 | 1.25 |
310.40 | 1.54 | 1.54 |
198.27 | 2.40 | 2.40 |