Basic Information
ID: ALA5217172
Type: ADME
Description: Inhibition of human hepatic CYP3A4 using midazolam as substrate measured after 3 mins by LC-MS analysis relative to control
Organism: Homo sapiens
Tissue: Liver
Activity Charts
Bioactivity
Activity Types for Assay ALA5217172
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.41 | 2.86 | 2.86 |
| 463.15 | 4.09 | 4.09 |
| 388.04 | 2.44 | 2.44 |
| 387.05 | 2.35 | 2.35 |
| 272.31 | 1.12 | 1.12 |
| 317.30 | 1.03 | 1.03 |
| 379.23 | 1.11 | 1.11 |
| 290.33 | 1.22 | 1.22 |