Basic Information
ID: ALA5217267
Type: Binding
Description: Induction of AKT degradation in MS21-resistant human SW620 cells harboring KRAS/BRAF mutant assessed as reduction in total AKT level at 1 uM preincubated with 3-(3-(4-(amino(cyclobutyl)methyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SW620
Activity Charts
Bioactivity
Activity Types for Assay ALA5217267
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1114.47 |