Basic Information
ID: ALA5217287
Type: Binding
Description: Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescence microplate reader assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Matrix metalloproteinase 13(ALA280)
Document: ALA5214964
Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescence microplate reader assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5217287
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.59 | 2.45 | 2.45 |
| 457.58 | 2.49 | 2.49 |
| 487.60 | 1.85 | 1.85 |
| 487.58 | 3.03 | 3.03 |
| 485.63 | 3.27 | 3.27 |
| 561.63 | 3.98 | 3.98 |
| 489.57 | 3.94 | 3.94 |
| 525.57 | 3.42 | 3.42 |
| 487.60 | 1.85 | 1.85 |
| 501.61 | 3.38 | 3.38 |
| 484.65 | 3.06 | 3.06 |
| 471.58 | 3.80 | 3.80 |
| 549.67 | 2.78 | 2.78 |
| 511.67 | 3.80 | 3.80 |
| 510.69 | 3.77 | 3.77 |
| 500.62 | 2.95 | 2.95 |
| 543.64 | 3.84 | 3.84 |
| 486.59 | 2.61 | 2.61 |
| 518.61 | 3.09 | 3.09 |
| 505.57 | 3.17 | 3.17 |
| 511.67 | 3.80 | 3.80 |
| 470.62 | 2.85 | 2.85 |
| 567.66 | 2.92 | 2.92 |
| 470.62 | 2.84 | 2.84 |
| 510.69 | 3.77 | 3.77 |
| 510.69 | 3.77 | 3.77 |
| 484.65 | 3.11 | 3.11 |
| 504.58 | 2.75 | 2.75 |