Assay Report Card

Basic Information

ID: ALA5217405

Type: Binding

Description: Binding affinity to human G-quadruplex telomeric DNA F21T (5'-duplex FAM-GGGTTAGGGTTAGGGTTAGGG-TAM-3') assessed as stabilization by measuring change in melting temperature at 5 uM by FRET melting assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
335.370.850.85
479.546.126.12
780.520.880.88
399.320.950.95
450.546.026.02
446.516.306.30
290.373.663.66
380.401.291.29
322.371.611.61
296.29-0.01-0.01
520.634.674.67
848.765.245.24
524.674.014.01
552.633.293.29
808.490.160.16
402.596.786.78
604.636.036.03