Basic Information
ID: ALA5217639
Type: Binding
Description: Inhibition of wild type his tagged Escherichia coli K12 MurA using UDP-N-acetylglucosamine as substrate preincubated with substrate for 30 mins prior to compound addition for 15 mins followed by DTT and PEP addition and measured after 30 mins by malachite green based microplate reader analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA5217639
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 138.06 | -0.09 | -0.09 |
| 400.48 | 4.13 | 4.13 |
| 490.97 | 6.08 | 6.08 |
| 460.51 | 5.33 | 5.33 |
| 384.41 | 3.66 | 3.66 |
| 492.50 | 5.70 | 5.70 |
| 480.93 | 5.59 | 5.59 |
| 451.53 | 4.68 | 4.68 |
| 506.97 | 5.18 | 5.18 |
| 562.95 | 7.00 | 7.00 |
| 476.58 | 5.80 | 5.80 |
| 442.92 | 5.19 | 5.19 |
| 394.45 | 4.07 | 4.07 |
| 444.51 | 5.22 | 5.22 |
| 444.51 | 5.22 | 5.22 |
| 380.43 | 3.76 | 3.76 |
| 508.98 | 6.45 | 6.45 |
| 394.45 | 4.07 | 4.07 |
| 484.58 | 6.04 | 6.04 |
| 422.51 | 4.85 | 4.85 |
| 486.55 | 5.44 | 5.44 |
| 414.87 | 4.41 | 4.41 |
| 470.55 | 5.73 | 5.73 |
| 486.55 | 5.44 | 5.44 |
| 414.87 | 4.41 | 4.41 |
| 422.51 | 4.85 | 4.85 |
| 494.96 | 5.98 | 5.98 |
| 395.44 | 3.46 | 3.46 |
| 410.45 | 3.77 | 3.77 |
| 460.51 | 4.93 | 4.93 |
| 474.54 | 5.23 | 5.23 |
| 524.52 | 6.45 | 6.45 |
| 490.97 | 6.08 | 6.08 |
| 476.58 | 5.80 | 5.80 |
| 430.49 | 4.91 | 4.91 |
| 384.46 | 3.49 | 3.49 |
| 472.52 | 5.55 | 5.55 |
| 535.42 | 6.19 | 6.19 |
| 510.96 | 4.95 | 4.95 |
| 456.52 | 5.43 | 5.43 |
| 470.55 | 5.73 | 5.73 |