Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and meas...

Basic Information

ID: ALA5217731

Type: Binding

Description: Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and measured by colorimetric method based esterolytic assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Complement factor D(ALA2176771)

Document: ALA5214987

Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and measured by colorimetric method based esterolytic assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5217731

IC50

Total(56)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
484.92	2.19	2.19
483.33	1.92	1.92
465.43	3.68	3.68
378.23	1.67	1.67
471.32	1.92	1.92
459.91	2.48	2.48
403.24	1.54	1.54
430.30	3.22	3.22
459.91	2.48	2.48
425.88	2.42	2.42
428.29	2.82	2.82
598.08	3.69	3.69
485.95	3.02	3.02
473.94	2.87	2.87
515.93	2.02	2.02
487.92	1.73	1.73
461.88	1.06	1.06
471.92	2.63	2.63
431.86	1.70	1.70
615.11	2.70	2.70
439.45	1.40	1.40
693.16	3.72	3.72
457.89	2.24	2.24
620.03	3.50	3.50
501.90	1.93	1.93
457.89	2.24	2.24
515.93	2.02	2.02
475.91	1.46	1.46
501.90	1.93	1.93
473.89	1.94	1.94
421.25	0.77	0.77
499.97	3.41	3.41
620.03	3.50	3.50
413.28	2.89	2.89
459.91	2.53	2.53
443.87	2.56	2.56
477.90	2.43	2.43
403.24	1.54	1.54
445.88	2.09	2.09
517.95	2.27	2.27
425.42	1.61	1.61
625.10	2.55	2.55
488.32	2.67	2.67
463.87	2.04	2.04
571.05	3.61	3.61
514.00	3.80	3.80
572.04	3.16	3.16
417.83	1.36	1.36
473.89	1.94	1.94
487.92	1.73	1.73
573.02	3.58	3.58
627.12	2.79	2.79
431.29	2.12	2.12
419.28	1.60	1.60
479.46	3.99	3.99