Basic Information
ID: ALA5217731
Type: Binding
Description: Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and measured by colorimetric method based esterolytic assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5217731
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 484.92 | 2.19 | 2.19 |
| 483.33 | 1.92 | 1.92 |
| 465.43 | 3.68 | 3.68 |
| 378.23 | 1.67 | 1.67 |
| 471.32 | 1.92 | 1.92 |
| 459.91 | 2.48 | 2.48 |
| 403.24 | 1.54 | 1.54 |
| 430.30 | 3.22 | 3.22 |
| 459.91 | 2.48 | 2.48 |
| 425.88 | 2.42 | 2.42 |
| 428.29 | 2.82 | 2.82 |
| 598.08 | 3.69 | 3.69 |
| 485.95 | 3.02 | 3.02 |
| 473.94 | 2.87 | 2.87 |
| 515.93 | 2.02 | 2.02 |
| 487.92 | 1.73 | 1.73 |
| 461.88 | 1.06 | 1.06 |
| 471.92 | 2.63 | 2.63 |
| 431.86 | 1.70 | 1.70 |
| 615.11 | 2.70 | 2.70 |
| 439.45 | 1.40 | 1.40 |
| 693.16 | 3.72 | 3.72 |
| 457.89 | 2.24 | 2.24 |
| 620.03 | 3.50 | 3.50 |
| 501.90 | 1.93 | 1.93 |
| 457.89 | 2.24 | 2.24 |
| 515.93 | 2.02 | 2.02 |
| 475.91 | 1.46 | 1.46 |
| 501.90 | 1.93 | 1.93 |
| 473.89 | 1.94 | 1.94 |
| 421.25 | 0.77 | 0.77 |
| 499.97 | 3.41 | 3.41 |
| 620.03 | 3.50 | 3.50 |
| 413.28 | 2.89 | 2.89 |
| 459.91 | 2.53 | 2.53 |
| 443.87 | 2.56 | 2.56 |
| 477.90 | 2.43 | 2.43 |
| 403.24 | 1.54 | 1.54 |
| 445.88 | 2.09 | 2.09 |
| 517.95 | 2.27 | 2.27 |
| 425.42 | 1.61 | 1.61 |
| 625.10 | 2.55 | 2.55 |
| 488.32 | 2.67 | 2.67 |
| 463.87 | 2.04 | 2.04 |
| 571.05 | 3.61 | 3.61 |
| 514.00 | 3.80 | 3.80 |
| 572.04 | 3.16 | 3.16 |
| 417.83 | 1.36 | 1.36 |
| 473.89 | 1.94 | 1.94 |
| 487.92 | 1.73 | 1.73 |
| 573.02 | 3.58 | 3.58 |
| 627.12 | 2.79 | 2.79 |
| 431.29 | 2.12 | 2.12 |
| 419.28 | 1.60 | 1.60 |
| 479.46 | 3.99 | 3.99 |