Basic Information
ID: ALA5217778
Type: Binding
Description: Reversible covalent inhibition of FGFR4 in human Hep3B cells assessed as reduction in pFGFR expression preincubated for 1 hr followed by compound washout prior to FGF19 stimulation for 10 min and measured for 0.5 to 4 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: Hep3B
Activity Charts
Bioactivity
Activity Types for Assay ALA5217778
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 673.36 | 5.30 | 5.30 |