Basic Information
ID: ALA5217834
Type: Binding
Description: Inhibition of NLRC4 inflammasome activation in LPS/flagellin-treated human THP-1 cells preincubated with LPS for 3 hrs followed by compound addition for 30 mins and further stimulated with flagellin for 90 min
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: NLR family CARD domain-containing protein 4(ALA4630857)
Document: ALA5214989
Inhibition of NLRC4 inflammasome activation in LPS/flagellin-treated human THP-1 cells preincubated with LPS for 3 hrs followed by compound addition for 30 mins and further stimulated with flagellin for 90 min: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5217834
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.52 | 1.35 | 1.35 |