Basic Information
ID: ALA5217920
Type: Binding
Description: Inhibition of full-length N-terminal His-tagged human c-Abl kinase (2 to 1130 residues) expressed in baculovirus expression system using Tk-substrate preincubated for 5 to 10 mins followed by substrate addition and measured after 40 mins by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5217920
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.53 | 6.36 | 6.36 |
| 543.55 | 7.74 | 7.74 |
| 590.65 | 6.22 | 6.22 |
| 528.54 | 6.96 | 6.96 |
| 528.54 | 6.96 | 6.96 |
| 504.57 | 7.26 | 7.26 |
| 560.62 | 6.21 | 6.21 |
| 558.56 | 6.97 | 6.97 |
| 528.54 | 6.96 | 6.96 |
| 548.61 | 6.46 | 6.46 |
| 528.54 | 6.87 | 6.87 |
| 478.53 | 5.99 | 5.99 |
| 561.61 | 5.61 | 5.61 |
| 584.60 | 8.15 | 8.15 |
| 578.60 | 8.11 | 8.11 |
| 558.56 | 6.88 | 6.88 |
| 546.53 | 7.01 | 7.01 |
| 578.60 | 8.02 | 8.02 |
| 500.61 | 6.73 | 6.73 |
| 546.53 | 7.10 | 7.10 |
| 528.54 | 6.87 | 6.87 |
| 529.53 | 6.26 | 6.26 |
| 554.57 | 8.14 | 8.14 |
| 578.61 | 6.35 | 6.35 |
| 546.60 | 6.22 | 6.22 |
| 528.54 | 6.87 | 6.87 |