Basic Information
ID: ALA5218088
Type: Binding
Description: Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as substrate by sequential chromatographic analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5218088
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.79 | 3.01 | 3.01 |
| 329.79 | 2.71 | 2.71 |
| 299.76 | 2.70 | 2.70 |
| 522.94 | 2.81 | 2.81 |
| 335.74 | 3.56 | 3.56 |
| 512.97 | 2.67 | 2.67 |
| 464.90 | 3.27 | 3.27 |
| 492.96 | 3.79 | 3.79 |
| 356.82 | 2.06 | 2.06 |
| 477.90 | 2.37 | 2.37 |
| 335.80 | 3.62 | 3.62 |
| 334.21 | 3.36 | 3.36 |
| 335.80 | 3.62 | 3.62 |
| 494.93 | 2.63 | 2.63 |
| 357.80 | 2.49 | 2.49 |
| 494.93 | 2.63 | 2.63 |
| 356.82 | 2.06 | 2.06 |
| 494.93 | 2.63 | 2.63 |
| 441.92 | 1.51 | 1.51 |
| 357.80 | 2.49 | 2.49 |
| 329.79 | 2.71 | 2.71 |
| 334.21 | 3.36 | 3.36 |
| 353.74 | 3.64 | 3.64 |
| 440.94 | 2.41 | 2.41 |
| 478.89 | 2.80 | 2.80 |
| 494.93 | 2.63 | 2.63 |
| 522.94 | 2.81 | 2.81 |
| 428.92 | 2.41 | 2.41 |
| 440.94 | 2.56 | 2.56 |
| 334.21 | 3.36 | 3.36 |
| 391.86 | 4.50 | 4.50 |