Basic Information
ID: ALA5218243
Type: Binding
Description: Mixed type inhibition of N-terminal His-tagged recombinant human PTP1B expressed in Escherichia coli assessed as reduction in Vmax with increase in Km using varying concentrations of pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by Lineweaver-Burk plot analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Protein-tyrosine phosphatase 1B(ALA335)
Document: ALA5215002
Mixed type inhibition of N-terminal His-tagged recombinant human PTP1B expressed in Escherichia coli assessed as reduction in Vmax with increase in Km using varying concentrations of pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by Lineweaver-Burk plot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5218243
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 580.50 | -2.47 | -2.47 |
| 432.38 | -0.81 | -0.81 |