Basic Information
ID: ALA5223240
Type: Binding
Description: Inhibition of recombinant SARS-CoV-2 Main protease expressed in Escherichia coli using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured every 30 sec for 10 mins by FRET assay
Format: BAO_0000019
Organism: Severe acute respiratory syndrome coronavirus 2
Target: Replicase polyprotein 1ab(ALA4523582)
Document: ALA5223064
Inhibition of recombinant SARS-CoV-2 Main protease expressed in Escherichia coli using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured every 30 sec for 10 mins by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5223240
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.50 | 1.86 | 1.86 |
| 452.56 | 2.45 | 2.45 |