Basic Information
ID: ALA5223850
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 mins in presence of NADPH regenerating system by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5223850
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.50 | 3.23 | 3.23 |
| 455.52 | 4.40 | 4.40 |
| 472.54 | 2.70 | 2.70 |
| 576.65 | 2.88 | 2.88 |
| 383.50 | 3.88 | 3.88 |
| 508.57 | 2.58 | 2.58 |
| 370.50 | 2.56 | 2.56 |
| 473.53 | 3.88 | 3.88 |
| 408.97 | 2.83 | 2.83 |
| 383.50 | 3.88 | 3.88 |
| 365.48 | 4.26 | 4.26 |
| 505.58 | 5.09 | 5.09 |
| 379.51 | 4.65 | 4.65 |
| 499.57 | 4.15 | 4.15 |
| 472.54 | 2.70 | 2.70 |
| 353.47 | 4.26 | 4.26 |
| 499.57 | 4.27 | 4.27 |