Basic Information
ID: ALA5223878
Type: Binding
Description: Activation of human recombinant 5HT4E receptor transfected in tsA201 cells co-transfected with human APP695 assessed as increase in sAPPalpha secretion at 10 uM preincubated with 5HT4 receptor antagonist, GR-113808 followed by incubation with compound for 30 mins by western blot analysis relative to control
Organism: Homo sapiens
Cell type: tsA201
Activity Charts
Bioactivity
Activity Types for Assay ALA5223878
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 473.53 | 3.88 | 3.88 |