Basic Information
ID: ALA5224086
Type: Binding
Description: Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ATP addition and further incubated for 15 mins by ADP-Glo reagent based assay
Organism: Homo sapiens
Cell type: Insect cell
Activity Charts
Bioactivity
Activity Types for Assay ALA5224086
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.72 | 3.08 | 3.08 |
| 534.70 | 3.77 | 3.77 |
| 574.77 | 4.69 | 4.69 |
| 530.70 | 3.37 | 3.37 |
| 442.59 | 3.79 | 3.79 |
| 426.54 | 3.16 | 3.16 |
| 530.70 | 3.37 | 3.37 |
| 439.58 | 4.43 | 4.43 |
| 444.94 | 4.16 | 4.16 |
| 440.57 | 3.50 | 3.50 |
| 527.69 | 3.73 | 3.73 |
| 413.54 | 3.90 | 3.90 |
| 443.57 | 3.26 | 3.26 |
| 526.70 | 4.61 | 4.61 |
| 512.68 | 3.86 | 3.86 |
| 529.71 | 3.97 | 3.97 |
| 541.72 | 4.12 | 4.12 |
| 449.52 | 4.29 | 4.29 |
| 413.54 | 4.04 | 4.04 |
| 469.61 | 4.44 | 4.44 |
| 427.53 | 2.89 | 2.89 |
| 537.67 | 1.95 | 1.95 |
| 571.62 | 2.71 | 2.71 |
| 441.60 | 4.68 | 4.68 |
| 498.65 | 3.83 | 3.83 |
| 538.55 | 3.63 | 3.63 |