Basic Information
ID: ALA5224179
Type: Binding
Description: Inhibition of 6His-tagged TEV protease fused human SHP2 (1 to 525 residues) expressed in Escherichia coli BL21 star (DE3) using DiFMUP as substrate preincubated for 30 to 60 mins followed by substrate addition and measured after 30 mins by fluorescence based microplate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5224179
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.87 | 4.13 | 4.13 |
| 446.85 | 3.82 | 3.82 |
| 573.99 | 3.82 | 3.82 |