Assay Report Card

Basic Information

ID: ALA5225050

Type: Binding

Description: Inhibition of FGFR activation in FGF-stimulated human DMS-114 cells assessed as reduction in FRS2alpha phosphorylation at 10 to 1000 nM preincubated with compound for 4 hrs followed by FGF stimulation for 30 mins by Western blot analysis

Organism: Homo sapiens

Cell type: DMS-114

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
463.583.653.65