Basic Information
ID: ALA5225054
Type: Binding
Description: PROTAC activity at FGFR1/VHL in FGF-stimulated human DMS-114 cells assessed as FGFR1 degradation by measuring reduction in FRS2alpha phosphorylation at 10 to 1000 nM preincubated with compound for 4 hrs followed by FGF stimulation for 30 mins by Western blot analysis
Organism: Homo sapiens
Cell type: DMS-114
Activity Charts
Bioactivity
Activity Types for Assay ALA5225054
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1125.41 |