Basic Information
ID: ALA5225095
Type: Binding
Description: Inhibition of SARS-CoV-2 BetaCoV/Wuhan/WIV04/2019 Main protease expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQ/SGFRKME(Edans) as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by FRET assay
Format: BAO_0000019
Organism: Severe acute respiratory syndrome coronavirus 2
Strain: BetaCoV/Wuhan/WIV04/2019
Target: Replicase polyprotein 1ab(ALA4523582)
Document: ALA5223130
Inhibition of SARS-CoV-2 BetaCoV/Wuhan/WIV04/2019 Main protease expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQ/SGFRKME(Edans) as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5225095
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.57 | 1.50 | 1.50 |
| 482.58 | 2.89 | 2.89 |