Assay Report Card

Basic Information

ID: ALA5225585

Type: Binding

Description: Inhibition of ovine COX-1 using arachidonic acid as substrate assessed as reduction in 12-HHT formation by measuring residual activity at 10 uM preincubated for 5 mins followed by substrate addition and measured after 5 mins by RP-HPLC analysis relative to control

Organism: Ovis aries

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
421.915.065.06
451.355.475.47
452.335.595.59
442.335.415.41