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Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins fol...

Basic Information

ID: ALA5225647

Type: Binding

Description: Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis

Format: BAO_0000357

Organism: Homo sapiens

Target:  NADP-dependent malic enzyme, mitochondrial(ALA6182)

Document:  ALA5223163

Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
351.411.851.85
352.343.093.09
295.301.431.43
339.442.802.80
297.361.681.68
341.412.082.08
345.832.722.72
312.371.461.46
357.432.942.94
308.382.752.75
388.384.394.39
338.453.413.41
297.361.681.68
297.362.752.75
330.822.942.94
312.372.122.12
317.412.132.13
385.462.092.09
311.382.072.07
329.382.212.21
364.373.303.30
316.322.672.67
296.372.282.28
298.351.071.07
382.503.853.85
310.402.722.72
373.883.463.46
367.473.283.28
314.362.422.42
296.373.253.25
310.402.672.67
311.392.152.15
393.513.803.80
383.493.253.25