Basic Information
ID: ALA5225648
Type: Binding
Description: Inhibition of His-tagged human recombinant full length ME2 using L-malate and beta-NAD+ as substrate preincubated with enzyme for 5 mins followed by beta-NAD+ challenge and incubated under shaking for 5 mins followed by incubation for 2 hrs without shaking by resorufin dye based fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5225648
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.41 | 1.85 | 1.85 |
| 352.34 | 3.09 | 3.09 |
| 295.30 | 1.43 | 1.43 |
| 339.44 | 2.80 | 2.80 |
| 297.36 | 1.68 | 1.68 |
| 341.41 | 2.08 | 2.08 |
| 345.83 | 2.72 | 2.72 |
| 312.37 | 1.46 | 1.46 |
| 357.43 | 2.94 | 2.94 |
| 308.38 | 2.75 | 2.75 |
| 388.38 | 4.39 | 4.39 |
| 338.45 | 3.41 | 3.41 |
| 297.36 | 1.68 | 1.68 |
| 297.36 | 2.75 | 2.75 |
| 330.82 | 2.94 | 2.94 |
| 312.37 | 2.12 | 2.12 |
| 317.41 | 2.13 | 2.13 |
| 385.46 | 2.09 | 2.09 |
| 311.38 | 2.07 | 2.07 |
| 329.38 | 2.21 | 2.21 |
| 364.37 | 3.30 | 3.30 |
| 316.32 | 2.67 | 2.67 |
| 296.37 | 2.28 | 2.28 |
| 298.35 | 1.07 | 1.07 |
| 382.50 | 3.85 | 3.85 |
| 373.88 | 3.46 | 3.46 |
| 367.47 | 3.28 | 3.28 |
| 314.36 | 2.42 | 2.42 |
| 310.40 | 2.67 | 2.67 |
| 311.39 | 2.15 | 2.15 |
| 393.51 | 3.80 | 3.80 |
| 383.49 | 3.25 | 3.25 |