Basic Information
ID: ALA5225653
Type: Binding
Description: Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate at 10 uM preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5225653
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 373.48 | 1.95 | 1.95 |
| 325.41 | 2.37 | 2.37 |
| 295.38 | 3.34 | 3.34 |
| 313.38 | 2.50 | 2.50 |
| 296.37 | 2.28 | 2.28 |
| 324.38 | 2.28 | 2.28 |
| 311.38 | 2.07 | 2.07 |
| 339.40 | 1.70 | 1.70 |
| 296.37 | 2.28 | 2.28 |
| 310.40 | 2.72 | 2.72 |
| 296.37 | 3.25 | 3.25 |