Basic Information
ID: ALA5225711
Type: Binding
Description: Protac activity at CRBN/MEK1/2 in human A549 cells assessed as MEK1/2 degradation at 10 uM incubated for 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA5225711
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 915.96 | 4.06 | 4.06 |
| 960.01 | 4.07 | 4.07 |
| 889.90 | 4.18 | 4.18 |
| 933.95 | 4.20 | 4.20 |
| 845.85 | 4.16 | 4.16 |
| 827.86 | 4.02 | 4.02 |
| 978.00 | 4.21 | 4.21 |
| 871.91 | 4.04 | 4.04 |