Basic Information
ID: ALA5225713
Type: Binding
Description: Protac activity at CRBN/MEK1/2 in human A549 cells assessed as MEK1/2 degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA5225713
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 817.79 | 4.07 | 4.07 |
| 831.81 | 4.46 | 4.46 |
| 859.87 | 5.24 | 5.24 |
| 873.90 | 5.63 | 5.63 |
| 845.84 | 4.85 | 4.85 |