Basic Information
ID: ALA5225714
Type: Binding
Description: Protac activity at VHL/MEK1/2 in human A549 cells assessed as MEK1/2 degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA5225714
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 989.14 | 6.83 | 6.83 |
| 1013.23 | ||
| 1045.25 | ||
| 1017.19 | ||
| 971.15 | 6.69 | 6.69 |
| 1083.37 | ||
| 1069.34 | ||
| 1003.17 | ||
| 1031.22 |