Basic Information
ID: ALA5225881
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against mouse RAW264.7 cells to IC50 for antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta level
Format: BAO_0000219
Target: Unchecked(ALA612545)
Document: ALA5223173
Selectivity index, ratio of CC50 for cytotoxicity against mouse RAW264.7 cells to IC50 for antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta level: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5225881
Ratio CC50/IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.23 | 7.23 |
| 478.72 | 7.31 | 7.31 |
| 591.88 | 7.12 | 7.12 |
| 575.88 | 7.78 | 7.78 |
| 585.67 | 8.18 | 8.18 |
| 562.84 | 8.13 | 8.13 |
| 598.32 | 7.71 | 7.71 |
| 552.80 | 6.31 | 6.31 |
| 558.25 | 6.74 | 6.74 |
| 572.28 | 7.13 | 7.13 |
| 598.32 | 7.71 | 7.71 |
| 549.84 | 7.34 | 7.34 |
| 584.87 | 6.83 | 6.83 |
| 536.76 | 6.87 | 6.87 |
| 596.85 | 9.53 | 9.53 |
| 534.79 | 7.35 | 7.35 |
| 550.83 | 7.55 | 7.55 |
| 584.29 | 7.32 | 7.32 |