Basic Information
ID: ALA5225884
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse bone-marrow derived macrophage cells to IC50 for anti-osteoclastogensis activity in BALB/c mouse bone marrow macrophage cells assessed as inhibition of RANKL/M-CSF-induced osteoclastogenesis
Format: BAO_0000219
Target: Unchecked(ALA612545)
Document: ALA5223173
Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse bone-marrow derived macrophage cells to IC50 for anti-osteoclastogensis activity in BALB/c mouse bone marrow macrophage cells assessed as inhibition of RANKL/M-CSF-induced osteoclastogenesis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5225884
Ratio CC50/IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.23 | 7.23 |
| 575.88 | 7.78 | 7.78 |
| 585.67 | 8.18 | 8.18 |
| 598.32 | 7.71 | 7.71 |
| 558.25 | 6.74 | 6.74 |
| 572.28 | 7.13 | 7.13 |
| 598.32 | 7.71 | 7.71 |
| 584.29 | 7.32 | 7.32 |