Basic Information
ID: ALA5226009
Type: Binding
Description: Inverse agonist activity at 6His-tagged RORC2 LBD (unknown origin) expressed in Escherichia coli assessed as inhibition of biotinylated SRC1-2 derived CPSSHSSLTERHKILHRLLQEGSPS-NH2 containing LXXLL coactivator peptide incubated for 3 hrs by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5226009
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 439.55 | 2.11 | 2.11 |
| 452.60 | 2.72 | 2.72 |
| 407.58 | 2.98 | 2.98 |
| 462.57 | 4.48 | 4.48 |
| 437.58 | 3.26 | 3.26 |
| 442.03 | 3.63 | 3.63 |
| 491.60 | 4.30 | 4.30 |
| 477.58 | 3.91 | 3.91 |
| 423.55 | 2.95 | 2.95 |
| 423.55 | 2.87 | 2.87 |
| 432.59 | 2.85 | 2.85 |
| 425.57 | 3.12 | 3.12 |
| 438.57 | 2.38 | 2.38 |