Basic Information
ID: ALA5226255
Type: Binding
Description: Allosteric inhibition of SHP2 in human KYSE-520 cells assessed as inhibition of ERK phosphorylation incubated for 2 hrs by TR-FRET assay
Organism: Homo sapiens
Cell type: KYSE-520 cell line
Activity Charts
Bioactivity
Activity Types for Assay ALA5226255
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.44 | 3.24 | 3.24 |
| 449.51 | 4.02 | 4.02 |
| 395.41 | 2.85 | 2.85 |
| 479.01 | 3.98 | 3.98 |
| 497.55 | 4.76 | 4.76 |
| 409.44 | 3.11 | 3.11 |
| 493.04 | 4.44 | 4.44 |
| 464.00 | 4.40 | 4.40 |
| 465.51 | 3.25 | 3.25 |
| 395.41 | 2.85 | 2.85 |