Basic Information
ID: ALA5227013
Type: Binding
Description: Inhibition of mouse ADAM17 expressed in HEK293 cells overexpressed with ACE2 assessed as inhibition of ACE2 shedding incubated for 65 mins in presence of PMA by immunoblotting assay
Format: BAO_0000219
Organism: Mus musculus
Cell type: HEK293
Target: ADAM17(ALA4379)
Document: ALA5226291
Inhibition of mouse ADAM17 expressed in HEK293 cells overexpressed with ACE2 assessed as inhibition of ACE2 shedding incubated for 65 mins in presence of PMA by immunoblotting assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5227013
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.54 | 1.41 | 1.41 |
| 415.54 | -0.35 | -0.35 |