Basic Information
ID: ALA5227706
Type: Binding
Description: Inhibition of human ASIC1a in HEK293 cells assessed as inward proton-gated current at pH 6.0 incubated with compound followed by PcTx1 addition by patch-clamp electrophysiology
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5227706
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.40 | 2.71 | 2.71 |
| 436.37 | 2.70 | 2.70 |
| 434.94 | 2.65 | 2.65 |
| 736.63 | 2.91 | 2.91 |
| 370.50 | 5.14 | 5.14 |
| 602.34 | 1.51 | 1.51 |
| 359.79 | 2.96 | 2.96 |
| 383.25 | 3.32 | 3.32 |
| 630.51 | 1.39 | 1.39 |
| 461.36 | 1.38 | 1.38 |
| 556.52 | 4.23 | 4.23 |