Basic Information
ID: ALA5228279
Type: Binding
Description: Inhibition of PARP-1 (unknown origin) using biotinylated NAD and NAD as substrate assessed as inhibition of auto-PARsylation incubated for 150 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5228279
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.34 | 2.83 | 2.83 |
| 298.34 | 1.80 | 1.80 |
| 286.31 | 2.66 | 2.66 |
| 280.33 | 2.58 | 2.58 |
| 312.37 | 2.19 | 2.19 |
| 267.33 | 2.99 | 2.99 |
| 283.33 | 2.23 | 2.23 |
| 267.33 | 2.99 | 2.99 |
| 296.33 | 1.82 | 1.82 |
| 286.31 | 2.66 | 2.66 |
| 281.36 | 3.30 | 3.30 |
| 298.34 | 1.80 | 1.80 |
| 268.32 | 2.52 | 2.52 |
| 300.38 | 3.19 | 3.19 |
| 302.76 | 3.18 | 3.18 |
| 282.34 | 2.83 | 2.83 |
| 312.37 | 2.19 | 2.19 |
| 326.40 | 2.85 | 2.85 |
| 298.34 | 2.01 | 2.01 |
| 284.32 | 1.62 | 1.62 |
| 304.30 | 2.80 | 2.80 |
| 283.33 | 2.23 | 2.23 |
| 283.33 | 2.23 | 2.23 |