Assay Report Card

Basic Information

ID: ALA5228348

Type: Functional

Description: In vivo inhibition of Wnt pathway in Hsd athymic nude mouse xenografted with human DLD1 cells assessed as increase in axin2 protein level in tumor at 10 to 30 mg/kg, po administered as single dose and measured after 18 hrs

Organism: Mus musculus

Strain: Hsd athymic nude

Cell type: DLD-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
282.342.832.83