Basic Information
ID: ALA5228492
Type: ADME
Description: Substrate activity at p-glycoprotein (unknown origin) expressed in pig LLC-PK1 cells coexpressing MDR1 assessed as efflux ratio at apparent permeability across basolateral to apical side to apparent permeability across apical to basolateral side at 1 uM measured after 1 hr by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: LLC-PK1
Target: P-glycoprotein 1(ALA4302)
Document: ALA5226336
Substrate activity at p-glycoprotein (unknown origin) expressed in pig LLC-PK1 cells coexpressing MDR1 assessed as efflux ratio at apparent permeability across basolateral to apical side to apparent permeability across apical to basolateral side at 1 uM measured after 1 hr by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5228492
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.42 | 3.12 | 3.12 |
| 288.37 | 2.34 | 2.34 |
| 339.41 | 3.64 | 3.64 |
| 353.44 | 3.66 | 3.66 |
| 325.39 | 3.33 | 3.33 |
| 353.44 | 3.66 | 3.66 |