Basic Information
ID: ALA5229239
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis recombinant PknB (1 to 331 residues) expressed in Escherichia coli BL21-Rosetta cells using GarA and ATP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 1 hr by ATP-competitive biochemical assay
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA5229239
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.46 | 3.70 | 3.70 |
| 414.44 | 4.05 | 4.05 |
| 443.48 | 4.09 | 4.09 |
| 458.44 | 4.57 | 4.57 |
| 463.51 | 5.81 | 5.81 |
| 443.47 | 4.67 | 4.67 |
| 438.46 | 4.53 | 4.53 |
| 438.46 | 4.53 | 4.53 |
| 431.44 | 4.80 | 4.80 |
| 458.44 | 4.57 | 4.57 |
| 427.47 | 4.97 | 4.97 |
| 447.89 | 5.31 | 5.31 |
| 448.88 | 4.71 | 4.71 |
| 413.45 | 4.66 | 4.66 |
| 519.58 | 5.66 | 5.66 |
| 431.44 | 4.80 | 4.80 |
| 447.89 | 5.31 | 5.31 |
| 750.79 | 1.27 | 1.27 |