Basic Information
ID: ALA5229862
Type: Binding
Description: Inhibition of His tagged SARS-CoV-2 PLpro using Z-RLRGG-AMC as substrate assessed as substrate cleavage at 100 uM preincubated for 60 mins followed by substrate addition and measured every 3 mins for 72 mins by fluorescence based assay relative to control
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5229862
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.34 | 2.69 | 2.69 |
| 266.34 | 4.22 | 4.22 |
| 305.42 | 3.79 | 3.79 |
| 482.44 | 2.40 | 2.40 |
| 266.34 | 4.22 | 4.22 |
| 304.30 | 2.05 | 2.05 |
| 482.44 | 2.36 | 2.36 |
| 337.46 | 4.24 | 4.24 |
| 413.48 | 3.69 | 3.69 |
| 362.42 | 2.32 | 2.32 |
| 343.47 | 4.96 | 4.96 |
| 468.51 | 5.44 | 5.44 |
| 369.49 | 3.94 | 3.94 |
| 446.46 | 4.59 | 4.59 |
| 397.43 | 2.93 | 2.93 |
| 294.70 | 1.91 | 1.91 |
| 409.48 | 4.73 | 4.73 |
| 408.50 | 3.99 | 3.99 |
| 410.50 | 3.10 | 3.10 |