Basic Information
ID: ALA5232376
Type: Binding
Description: Induction of stabilisation of human CFTR F508 deletion mutant expressed in human CFBE41o- cells assessed as VX-809-dependent maturation by measuring banc C at 10 uM measured after 24 hrs by western blotting assay relative to VX-809
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CFBE41o-
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA5230148
Induction of stabilisation of human CFTR F508 deletion mutant expressed in human CFBE41o- cells assessed as VX-809-dependent maturation by measuring banc C at 10 uM measured after 24 hrs by western blotting assay relative to VX-809: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5232376
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.76 | 2.75 | 2.75 |