Basic Information
ID: ALA5232379
Type: Binding
Description: Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incubated for 16 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: Huh-7
Activity Charts
Bioactivity
Activity Types for Assay ALA5232379
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.85 | 8.87 | 8.87 |
| 420.63 | 5.11 | 5.11 |
| 586.86 | 7.79 | 7.79 |
| 552.41 | 7.14 | 7.14 |
| 542.38 | 6.73 | 6.73 |
| 609.53 | 7.35 | 7.35 |
| 585.87 | 8.40 | 8.40 |
| 575.83 | 7.99 | 7.99 |
| 605.57 | 7.52 | 7.52 |
| 598.55 | 7.78 | 7.78 |
| 610.59 | 7.65 | 7.65 |
| 600.98 | 7.99 | 7.99 |
| 551.43 | 7.74 | 7.74 |
| 581.55 | 7.04 | 7.04 |
| 551.43 | 7.74 | 7.74 |
| 569.42 | 7.88 | 7.88 |
| 625.99 | 7.86 | 7.86 |
| 599.90 | 8.71 | 8.71 |
| 585.87 | 8.40 | 8.40 |
| 610.88 | 8.27 | 8.27 |
| 585.87 | 8.40 | 8.40 |
| 594.59 | 7.95 | 7.95 |
| 585.51 | 6.87 | 6.87 |
| 601.97 | 7.38 | 7.38 |
| 615.00 | 8.30 | 8.30 |
| 585.87 | 8.40 | 8.40 |
| 621.57 | 7.22 | 7.22 |
| 630.32 | 8.51 | 8.51 |
| 619.42 | 8.76 | 8.76 |