ID: ALA5232380
Type: Binding
Description: Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incubated for 16 hrs by luciferase reporter gene assay relative to OCA
Organism: Homo sapiens
Cell type: Huh-7
Bioactivity
Activity Types for Assay ALA5232380
Efficacy
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
542.85 | 8.87 | 8.87 |
420.63 | 5.11 | 5.11 |
586.86 | 7.79 | 7.79 |
552.41 | 7.14 | 7.14 |
542.38 | 6.73 | 6.73 |
609.53 | 7.35 | 7.35 |
585.87 | 8.40 | 8.40 |
575.83 | 7.99 | 7.99 |
605.57 | 7.52 | 7.52 |
598.55 | 7.78 | 7.78 |
610.59 | 7.65 | 7.65 |
600.98 | 7.99 | 7.99 |
551.43 | 7.74 | 7.74 |
581.55 | 7.04 | 7.04 |
551.43 | 7.74 | 7.74 |
569.42 | 7.88 | 7.88 |
625.99 | 7.86 | 7.86 |
599.90 | 8.71 | 8.71 |
585.87 | 8.40 | 8.40 |
610.88 | 8.27 | 8.27 |
585.87 | 8.40 | 8.40 |
594.59 | 7.95 | 7.95 |
585.51 | 6.87 | 6.87 |
601.97 | 7.38 | 7.38 |
615.00 | 8.30 | 8.30 |
585.87 | 8.40 | 8.40 |
621.57 | 7.22 | 7.22 |
630.32 | 8.51 | 8.51 |
619.42 | 8.76 | 8.76 |