Assay Report Card

Basic Information

ID: ALA5232389

Type: Functional

Description: In vivo agonist activity at FXR in C57BL/6J mouse assessed as downregulation of CYP7A1 mRNA expression in liver at 30 mg/kg, po measured after 6 hrs by qRT-PCR analysis

Organism: Mus musculus

Strain: C57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
420.635.115.11