Assay Report Card

Basic Information

ID: ALA5232390

Type: Functional

Description: In vivo agonist activity at FXR in C57BL/6J mouse assessed as downregulation of CYP8B1 mRNA expression in liver at 10 mg/kg, po measured after 6 hrs by qRT-PCR analysis

Organism: Mus musculus

Strain: C57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
625.997.867.86
610.888.278.27