Assay Report Card

Basic Information

ID: ALA5232901

Type: Binding

Description: Selectivity index, ratio of Ki for inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed as inhibition constant to Ki for binding affinity to BCL-xL (unknown origin) assessed as inhibition constant

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
504.006.006.00
504.006.006.00
425.514.614.61
516.026.296.29
399.474.094.09
441.514.734.73
349.412.942.94
425.514.614.61
399.474.094.09
538.026.556.55
349.412.942.94