Basic Information
ID: ALA5233102
Type: Binding
Description: Inhibition of 6 His-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE3) cells using 9,10-phenanthrenequinone as substrate assessed as substrate reduction by measuring change in NADPH fluorescence at 33.3 uM incubated for 30 mins by fluorescence spectroscopic analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5233102
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.28 | 3.07 | 3.07 |
| 446.59 | 2.64 | 2.64 |
| 430.59 | 3.88 | 3.88 |
| 444.58 | 2.86 | 2.86 |
| 430.59 | 3.67 | 3.67 |
| 544.69 | 4.08 | 4.08 |
| 428.58 | 3.89 | 3.89 |
| 500.68 | 4.93 | 4.93 |
| 446.59 | 2.85 | 2.85 |